Synthesise Dmt

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And if I’d be interested in cookery I wouldn’t be asking questions on SM Melgar, indole itself can form a Grignard reagent of some sort: Since it is a pyrrole, the proton that lies on the nitrogen is actually fairly acidic, and so it can be deprotonated there to give a nitrogen-centered anion.

However, the C-3 carbon is also fairly acidic due to ring resonance influenced by the benzene ring, so alternatively indole can be deprotonated there as well.

You'd have to use an excess of HBr to brominate dimethyaminoethanol.

But once you have dimethylaminoethyl bromide, can you freebase it without a lot of quaternary amine polymer forming?

Although there is significant capacity for regeneration, the amount of PET reprocessed is much smaller than the amount that is recycled as resin.

I’m supposing this synthesis of DMT (or DET, where instead of DMAE DEAE would be used) : First, the indole would be converted to 3-bromoindole using the experimemtal method described in this paper: (NOTE: the experimental method using pyridine as a solvent and pyridium bromide perbromide or dioxane dibromide as a brominating agent) Then, the dimethylaminoethanol is converted to 2-Bromo-N, N-dimethylethanamine hydrobromide using hydrobromic acid.

The manufacture of polyester film, PBT, and other minor products such as cyclohexanedimethanol (CHDM), terephthaloyl chloride, and copolyester-ether elastomers accounts for the remainder of TPA/DMT consumption.

Increasing demand for polyester fibers will drive future consumption of TPA/DMT.

[Edited on 9-1-2018 by James Nilep] I have seen SM used for theoritacal discussions about illegal substances, that’s why I thought posting here would be appropriate, this is definitely not meant to be a discussion about “how do I make such and such illegal compound”, rather a theoretical question about an alternate synthesis pathway.

I think the jury is still out on whether this thread violates the SM guidelines...


Comments Synthesise Dmt

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