Through early biotechnology, the earliest farmers selected and bred the best suited crops, having the highest yields, to produce enough food to support a growing population.
As crops and fields became increasingly large and difficult to maintain, it was discovered that specific organisms and their by-products could effectively fertilize, restore nitrogen, and control pests.
Throughout the history of agriculture, farmers have inadvertently altered the genetics of their crops through introducing them to new environments and breeding them with other plants — one of the first forms of biotechnology.
These processes also were included in early fermentation of beer.
These processes were introduced in early Mesopotamia, Egypt, China and India, and still use the same basic biological methods.
In brewing, malted grains (containing enzymes) convert starch from grains into sugar and then adding specific yeasts to produce beer.Glycosylation influences activity, stability and immobilization of the feruloyl esterase 1a from Myceliophthora thermophila C. Martin L Johansson, R J Stokroos, R Banga, M K Hol, E A Mylanus et al.A large variety of microorganism is used that includes the naturally occurring microorganism, genetically modified organisms and some of the selected mutants.This has given rise to a huge scope for conduction research in industrial microbiology in both academic level as well as professional level.Su Re Tech is a interdisciplinary research project about utilizing agricultural and forestry byproducts to isolate high-value compounds such as antioxidants and pigments using "green and clean" technology.Examples of byproducts are onion waste, fruit press cakes, waste carrots and birch bark.Biotechnology is the research and development in the laboratory using bioinformatics for exploration, extraction, exploitation and production from any living organisms and any source of biomass by means of biochemical engineering where high value-added products could be planned (reproduced by biosynthesis, for example), forecasted, formulated, developed, manufactured, and marketed for the purpose of sustainable operations (for the return from bottomless initial investment on R & D) and gaining durable patents rights (for exclusives rights for sales, and prior to this to receive national and international approval from the results on animal experiment and human experiment, especially on the pharmaceutical branch of biotechnology to prevent any undetected side-effects or safety concerns by using the products).By contrast, bioengineering is generally thought of as a related field that more heavily emphasizes higher systems approaches (not necessarily the altering or using of biological materials directly) for interfacing with and utilizing living things.Relatedly, biomedical engineering is an overlapping field that often draws upon and applies biotechnology (by various definitions), especially in certain sub-fields of biomedical or chemical engineering such as tissue engineering, biopharmaceutical engineering, and genetic engineering.Although not normally what first comes to mind, many forms of human-derived agriculture clearly fit the broad definition of "'utilizing a biotechnological system to make products".